Research projects

Find out more about the research projects that St. Mark's Hospital Foundation support...

St Mark’s attracts specialists from across the globe to study and undertake research. Below are a few of the research areas that our fundraising helps to support:

  • The role of genetics in cancer
  • Minimally invasive surgical techniques
  • Improving patient involvement in decision making
  • Inflammatory Bowel Disease
  • Tissue engineering and artificial bowel development
  • Personalised medicine, utilizing genomics and gut microbiome
  • The use of 3D imaging to enhance surgical accuracy
  • Enhancing Colonoscopy and CT Colonography cancer diagnosis tools and expertise
  • Surgical Robotics Research programme
  • FAP genetics research

Major Research Projects


BiCyCLe is researching ways of boosting the immune system of bowel cancer patients to help them fight the disease. This research project seeks to gauge a better understanding of the key medical challenges such as sarcopenia, which is weight loss that occurs due to cancer.

Psychological Treatment of Chronic Abdominal Pain

Chronic abdominal pain is currently treated by prescribing mainly opiate based pain killers. In addition to being highly addictive they can also have many other detrimental side effects. The Foundation secured funding, in collaboration with Kings College and St George’s Hospital to carry out research into the psychological treatment of abdominal pain. Two psychological modalities are being investigated; Acceptance and Commitment Therapy, and Hypnotherapy, as potential treatments that could help reduce reliance on painkillers.


The accuracy levels for identifying pre-cancerous and cancerous growths by Computer Tomography (CT) Colonography vary widely throughout the UK. This level can be as little as 14% in some centres to 100% at St Mark’s.The PERFECTS research programme aims to train all CT Colonographers in the UK to a high standard of proficiency and to provide professional accreditation. This will mean that for frail and fearful people non-invasive CT Colonography may be provided.


Bowel cancer screening and surveillance has been carried out for many years in a standardised way. PROGRESS will investigate the application of cutting edge molecular pathology techniques, combined with results of colonoscopy, and an individuals family cancer history to more accurately predict who will develop bowel cancer and tailor the intensity of colonoscopies appropriately.

Contact Us

The Foundation is currently helping to fund the aforementioned and many other research projects. If you would like to find out more information on which projects require your continued support please contact Chief Executive Jason Bacon, on 020 8235 4042 or email